A cold sore is a painful blister that appears on the outside of the mouth close to or on the lips. Also known as fever blisters, cold sores develop due to herpes simplex virus type 1 (HSV-1) infections. The HSV-1 virus is highly contagious and spreads through oral contact. While HSV-1 often leads to blisters around the mouth, it can also infect the genitals and lead to genital herpes. Although there is no cure for HSV-1 infections, several treatment options can help reduce the healing time of cold sores and may even prevent them from appearing. Not all cold sores require treatment. Most cold sores heal on their own within 10 days. People should contact a doctor if their cold sore does not improve or worsens after they treat it with OTC or at-home remedies. People should also seek medical treatment if they have: a cold sore that lasts longer than 2 weeks, numerous cold sores at once, a cold sore near their eye, a weakened immune system(Credits: www.medicalnewstoday.com)